Seroepidemiological Survey of Human Visceral Leishmaniasis in Ilam Province, West of Iran In 2013
نویسندگان
چکیده
BACKGROUND Visceral leishmaniasis (VL) as one of the most important human parasitic disease is endemic in some parts of Iran. Several cases of VL have been reported recently in the Ilam Province. The current study aimed to assess the present status of human VL in the region. METHODS A random cluster sampling method was used to collect 456 serums samples from the children up to 12 years of age and 10% of adults living in urban and rural areas of the province. All the collected serum samples were tested by direct agglutination test (DAT) to detect anti- Leishmania infantum antibodies. RESULTS Of the examined 456 serum samples with direct agglutination test (DAT), only 21 (0.43%) sera showed anti- Leishmania antibodies at titers 1:400 and higher. Distribution of anti- Leishmania antibodies titers were: 1:400(n=4), 1:800(n=11), 1:1600(n=3), 1:3200(n=1), and 1:6400(n=1). Individuals with titers ≥1:3200 showed clinical signs and symptoms such as fever and splenomegaly. The highest and lowest seropositivity were observed in the age groups of 5-9 and >15 years old, respectively. There were no significant difference between the rate of seropositivity in males and females. CONCLUSION VL with a low prevalence circulates in some parts of Ilam province, particularly in the southern parts. Complementary studies should be needed to find animal reservoir hosts and vectors. Furthermore, health systems and physicians should pay particular attention to the disease.
منابع مشابه
Seroepidemiological investigation of visceral leishmaniasis in dogs of Ahvaz district, Iran
Visceral leishmaniasis is a parasitic infectious disease from dogs and canids to human that is caused by protozoans of the genus Leishmania. Information on the prevalence of canine leishmaniasis is necessary to define control measures for zoonotic leishmaniasis. This seroepidemiological survey was performed in dogs from Ahvaz district using by DAT and ELISA. Blood was randomly collected in 38 p...
متن کاملSeroepidemiological study of visceral Leishmaniasis (human infection) in East Myankooh area, in Lorestan Province by Direct Agglutination Test (DAT)
Background: Leishmaniasis is an infection caused by a protozoan of the genus Leishmania. This descriptive and cross-sectional study was done in order to determine the seroepidemiology of visceral leishmaniasis in East Myankooh area, in Lorestan Province during 2004 – 2005 time period. Materials and methods: This study was a descriptive, cross-sectional study. Multi stage sampling was performed...
متن کاملPreparation and evaluation of latex agglutination technique for diagnosis and seroepidemiological studies of visceral leishmaniasis
in this study which has been carried out from 1996 until 1997 soluble latex agglutination antigen was prepared from L, donovani,sudan(s-1) by culturing in special media,harvesting,and later solubilizing by freezing and thawing.the antigen were futher prepared by high speed centrifugation.after measurement of the protein (lowry method) concentration of the antigen was set at 2.2 mg/ml,the antige...
متن کاملSeroepidemiological study of canine visceral leishmaniasis in Meshkin shahr, Northwest of Iran
متن کامل
Seroepidemiologic Survey of Canine Visceral Leishmaniasis in Tehran and Alborz Provinces of Iran
BACKGROUND A two year seroepidemiological study was designed to find out the seroprevalence and risk factors of canine visceral leishmaniasis (CVL) among stray and owned dogs in Tehran and Alborz Provinces of Iran. METHODS Blood samples of 602 dogs living in 11 counties of Tehran and Alborz Provinces were taken by venipuncture in 2008-2010. After separation of blood sera, anti-leishmanial ant...
متن کامل